Crossover trials are clinical experiments in which participants are assigned randomly to a sequence of treatments and each participant serves as his/her own control in estimating the treatments’ effect.

The advantage of crossover is that it effectively doubles the number of people in a trial which makes it easier to obtain statistically significant results more quickly, and participants act as their own control since their data is analyzed by comparing participants to themselves – before the intervention and after each intervention period.

Essentially, the study participants are switched through the treatment groups (both test and reference formulations) after a washout period. This gives a greater set of results with fewer volunteers and in a more controlled way.

QUINTA-ANALYTICA who are experts in this approach go a step further and plan and design studies so that the washout period of one study is utilized as a confinement period for another. Combine this with the fact they’ve smartly constructed their clinical unit in two independent parts to allow for simultaneous studies, the outcome is an impressive set of quality results in a very short period.

Ready to start your next cross-over Bioavailability or Bioequivalence study? Get in touch!

Additional News

  • 19 December 2023

    Happy new year 2024

    As we bid farewell to 2023, it's time to express our deepest gratitude for the collaboration.

  • 4 December 2023

    Our new clinical unit in Ostrava comes to life

    It's a great pleasure to announce that after two years of hard work, the brand-new clinical unit in Ostrava with 36-beds capacity has been opened.

  • 3 October 2023

    Meet us at the heart of Pharma, CPHI 2023

    Quinta-Analytica is attending CPHI 2023 in Barcelona