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Biopharmaceutical analyses

 

Protein Purity

The evaluation of purity is a very important part of comprehensive characterization of protein- or peptide-based pharmaceutical substances as the presence of aggregates, residual nucleic acids or bacterial endotoxins can induce an adverse and potentially very serious immuno reaction in humans.

List of currently available analytical techniques

  • 1D gel electrophoresis
  • Size-exclusion chromatography
  • Capillary electrophoresis