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Biopharmaceutical analyses

 

Immunochemical properties

Assessment of immunochemical properties is essential especially when proteins of interest fall into category of antibodies. In that case, binding assays of a drug to specific antigens or well defined regions of antigens should be performed. Other important properties that need to be evaluated are the immunological response to the drug in living organism, and the possible neutralizing effects of produced antibodies after the administration of the drug.

List of currently available analytical techniques

  • ELISA (direct, indirect, sandwich, bridging)  
    • antigen-antibody binding assay
  • Western-Blot  
    • antigen-antibody binding
    • MW info